creb inhibitor 666 15 Search Results


666-15  (MedChemExpress)
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MedChemExpress 666-15
666 15, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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666-15  (Bio-Techne corporation)
93
Bio-Techne corporation 666-15
666 15, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
666-15 - by Bioz Stars, 2026-02
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creb inhibitor 666-15  (Toronto Research Chemicals)
90
Toronto Research Chemicals creb inhibitor 666-15
Pharmacologic dissection of LPA-induced cellular signaling pathways. HKC-8 cells were pretreated for 1 h with 666-15 <t>(CREB1</t> <t>inhibitor)</t> 10 μM in ( A ), JSH23 (NFκΒ inhibitor) 100 μM in ( B ), PD98059 (MEK/ERK inhibitor) 50 μM in ( C ), or SP600125 (JNK inhibitor) 50 μM in ( D ) and then activated with LPA at a final concentration of 10 μΜ for 4 h. mRNA-expression levels of the indicated secreted factors were quantified with RT-qPCR. The Cq values of each gene were normalized against the Cq values of B2M . Statistical analysis was performed with unpaired t -test or Welch’s test in the case of normal data and with Mann–Whitney in the case of non-normal data. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. See also .
Creb Inhibitor 666 15, supplied by Toronto Research Chemicals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/creb inhibitor 666-15/product/Toronto Research Chemicals
Average 90 stars, based on 1 article reviews
creb inhibitor 666-15 - by Bioz Stars, 2026-02
90/100 stars
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creb inhibitor 666-15  (Hycultec Inc)
90
Hycultec Inc creb inhibitor 666-15
Pharmacologic dissection of LPA-induced cellular signaling pathways. HKC-8 cells were pretreated for 1 h with 666-15 <t>(CREB1</t> <t>inhibitor)</t> 10 μM in ( A ), JSH23 (NFκΒ inhibitor) 100 μM in ( B ), PD98059 (MEK/ERK inhibitor) 50 μM in ( C ), or SP600125 (JNK inhibitor) 50 μM in ( D ) and then activated with LPA at a final concentration of 10 μΜ for 4 h. mRNA-expression levels of the indicated secreted factors were quantified with RT-qPCR. The Cq values of each gene were normalized against the Cq values of B2M . Statistical analysis was performed with unpaired t -test or Welch’s test in the case of normal data and with Mann–Whitney in the case of non-normal data. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. See also .
Creb Inhibitor 666 15, supplied by Hycultec Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/creb inhibitor 666-15/product/Hycultec Inc
Average 90 stars, based on 1 article reviews
creb inhibitor 666-15 - by Bioz Stars, 2026-02
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creb inhibitor 666-15  (Cayman Chemical)
90
Cayman Chemical creb inhibitor 666-15
Pharmacologic dissection of LPA-induced cellular signaling pathways. HKC-8 cells were pretreated for 1 h with 666-15 <t>(CREB1</t> <t>inhibitor)</t> 10 μM in ( A ), JSH23 (NFκΒ inhibitor) 100 μM in ( B ), PD98059 (MEK/ERK inhibitor) 50 μM in ( C ), or SP600125 (JNK inhibitor) 50 μM in ( D ) and then activated with LPA at a final concentration of 10 μΜ for 4 h. mRNA-expression levels of the indicated secreted factors were quantified with RT-qPCR. The Cq values of each gene were normalized against the Cq values of B2M . Statistical analysis was performed with unpaired t -test or Welch’s test in the case of normal data and with Mann–Whitney in the case of non-normal data. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. See also .
Creb Inhibitor 666 15, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/creb inhibitor 666-15/product/Cayman Chemical
Average 90 stars, based on 1 article reviews
creb inhibitor 666-15 - by Bioz Stars, 2026-02
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666-15, a selective inhibitor of cylic amp (camp)-responsive element-binding protein (creb)  (Cayman Chemical)
90
Cayman Chemical 666-15, a selective inhibitor of cylic amp (camp)-responsive element-binding protein (creb)
Pharmacologic dissection of LPA-induced cellular signaling pathways. HKC-8 cells were pretreated for 1 h with 666-15 <t>(CREB1</t> <t>inhibitor)</t> 10 μM in ( A ), JSH23 (NFκΒ inhibitor) 100 μM in ( B ), PD98059 (MEK/ERK inhibitor) 50 μM in ( C ), or SP600125 (JNK inhibitor) 50 μM in ( D ) and then activated with LPA at a final concentration of 10 μΜ for 4 h. mRNA-expression levels of the indicated secreted factors were quantified with RT-qPCR. The Cq values of each gene were normalized against the Cq values of B2M . Statistical analysis was performed with unpaired t -test or Welch’s test in the case of normal data and with Mann–Whitney in the case of non-normal data. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. See also .
666 15, A Selective Inhibitor Of Cylic Amp (Camp) Responsive Element Binding Protein (Creb), supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/666-15, a selective inhibitor of cylic amp (camp)-responsive element-binding protein (creb)/product/Cayman Chemical
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666-15, a selective inhibitor of cylic amp (camp)-responsive element-binding protein (creb) - by Bioz Stars, 2026-02
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Pharmacologic dissection of LPA-induced cellular signaling pathways. HKC-8 cells were pretreated for 1 h with 666-15 (CREB1 inhibitor) 10 μM in ( A ), JSH23 (NFκΒ inhibitor) 100 μM in ( B ), PD98059 (MEK/ERK inhibitor) 50 μM in ( C ), or SP600125 (JNK inhibitor) 50 μM in ( D ) and then activated with LPA at a final concentration of 10 μΜ for 4 h. mRNA-expression levels of the indicated secreted factors were quantified with RT-qPCR. The Cq values of each gene were normalized against the Cq values of B2M . Statistical analysis was performed with unpaired t -test or Welch’s test in the case of normal data and with Mann–Whitney in the case of non-normal data. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. See also .

Journal: International Journal of Molecular Sciences

Article Title: Lysophosphatidic Acid Is a Proinflammatory Stimulus of Renal Tubular Epithelial Cells

doi: 10.3390/ijms23137452

Figure Lengend Snippet: Pharmacologic dissection of LPA-induced cellular signaling pathways. HKC-8 cells were pretreated for 1 h with 666-15 (CREB1 inhibitor) 10 μM in ( A ), JSH23 (NFκΒ inhibitor) 100 μM in ( B ), PD98059 (MEK/ERK inhibitor) 50 μM in ( C ), or SP600125 (JNK inhibitor) 50 μM in ( D ) and then activated with LPA at a final concentration of 10 μΜ for 4 h. mRNA-expression levels of the indicated secreted factors were quantified with RT-qPCR. The Cq values of each gene were normalized against the Cq values of B2M . Statistical analysis was performed with unpaired t -test or Welch’s test in the case of normal data and with Mann–Whitney in the case of non-normal data. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. See also .

Article Snippet: LPAR1/3 inhibitor (Ki16425, Cat. no: HY-13285, MedChemExpress, Monmouth Junction, NJ, USA) was added at 10 μM; LPAR2 inhibitor (H2L5186303, Cat. no: 10-1452, Focus Biomolecules, Plymouth Meeting, PA, USA) was added at 10 μM; CREB inhibitor (666-15, Cat. no: A616443, Toronto Research Chemicals, North York, ON, Canada) was added at 10 μM; JNK inhibitor (SP600125, Cat. no: 420119, Calbiochem, San Diego, CA, USA) was added at 50 μM; NFκB inhibitor (JSH-23, Cat. no: HY-13982, MedChemExpress, Monmouth Junction, NJ, USA) was added at 100 μM; and MEK/ERK inhibitor (PD98059, Cat. no: 513000, Calbiochem, San Diego, CA, USA) was added at 50 μM.

Techniques: Dissection, Protein-Protein interactions, Concentration Assay, Expressing, Quantitative RT-PCR, MANN-WHITNEY